A Small β-Carboline Derivative "B-9-3" Modulates TGF-β Signaling Pathway Causing Tumor Regression in Vivo

• Hoofdauteurs: Hui Zhong (Auteur), Abdelkader Daoud (Auteur), Jichun Han (Auteur), Xiaohong An (Auteur), Caili Qiao (Auteur), Lanlan Duan (Auteur), Yichuan Wang (Auteur), Zhenfeng Chen (Auteur), Jia Zhou (Auteur), Jing Shang (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2018-07-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Targeting tumor microenvironment (TME) is crucial in order to overcome the anti-cancer therapy resistance. In this study, we report the antitumor activity of a newly synthesized β-carboline derivative "B-9-3." Here, this small molecule showed a promising antitumor activity in vivo along wi...