A Small β-Carboline Derivative "B-9-3" Modulates TGF-β Signaling Pathway Causing Tumor Regression in Vivo

• Asıl Yazarlar: Hui Zhong (Yazar), Abdelkader Daoud (Yazar), Jichun Han (Yazar), Xiaohong An (Yazar), Caili Qiao (Yazar), Lanlan Duan (Yazar), Yichuan Wang (Yazar), Zhenfeng Chen (Yazar), Jia Zhou (Yazar), Jing Shang (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2018-07-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Targeting tumor microenvironment (TME) is crucial in order to overcome the anti-cancer therapy resistance. In this study, we report the antitumor activity of a newly synthesized β-carboline derivative "B-9-3." Here, this small molecule showed a promising antitumor activity in vivo along wi...