Anion-Transport Mechanism of a Triazole-Bearing Derivative of Prodigiosine: A Candidate for Cystic Fibrosis Therapy

• Main Authors: Claudia Cossu (Author), Michele Fiore (Author), Debora Baroni (Author), Valeria Capurro (Author), Emanuela Caci (Author), Maria Garcia-Valverde (Author), Roberto Quesada (Author), Oscar Moran (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cystic fibrosis (CF) is a genetic lethal disease, originated from the defective function of the CFTR protein, a chloride and bicarbonate permeable transmembrane channel. CF mutations affect CFTR protein through a variety of molecular mechanisms which result in different functional defects. Current t...