Anion-Transport Mechanism of a Triazole-Bearing Derivative of Prodigiosine: A Candidate for Cystic Fibrosis Therapy

• Główni autorzy: Claudia Cossu (Autor), Michele Fiore (Autor), Debora Baroni (Autor), Valeria Capurro (Autor), Emanuela Caci (Autor), Maria Garcia-Valverde (Autor), Roberto Quesada (Autor), Oscar Moran (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2018-08-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Cystic fibrosis (CF) is a genetic lethal disease, originated from the defective function of the CFTR protein, a chloride and bicarbonate permeable transmembrane channel. CF mutations affect CFTR protein through a variety of molecular mechanisms which result in different functional defects. Current t...