Tolerogenic vaccine composited with islet-derived multipeptides and cyclosporin A induces pTreg and prevents Type 1 diabetes in murine model

Regulatory T cells (Tregs) play a crucial role in the control of the initiation and progression of type 1 diabetes (T1D). Various immunological interventions including those to ex vivo expansion Tregs transfer, in vivo induction of peripherally derived Treg (pTreg) have been considered as promising...

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Main Authors: Xian Zhou (Author), Shijie Zhang (Author), Fan Yu (Author), Gan Zhao (Author), Shuang Geng (Author), Wencong Yu (Author), Xuan-Yi Wang (Author), Bin Wang (Author)
Formato: Livro
Publicado em: Taylor & Francis Group, 2020-02-01T00:00:00Z.
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