Tolerogenic vaccine composited with islet-derived multipeptides and cyclosporin A induces pTreg and prevents Type 1 diabetes in murine model

• Автори: Xian Zhou (Автор), Shijie Zhang (Автор), Fan Yu (Автор), Gan Zhao (Автор), Shuang Geng (Автор), Wencong Yu (Автор), Xuan-Yi Wang (Автор), Bin Wang (Автор)
• Формат: Книга
• Опубліковано: Taylor & Francis Group, 2020-02-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Regulatory T cells (Tregs) play a crucial role in the control of the initiation and progression of type 1 diabetes (T1D). Various immunological interventions including those to ex vivo expansion Tregs transfer, in vivo induction of peripherally derived Treg (pTreg) have been considered as promising...