Tolerogenic vaccine composited with islet-derived multipeptides and cyclosporin A induces pTreg and prevents Type 1 diabetes in murine model

• Autores principales: Xian Zhou (Autor), Shijie Zhang (Autor), Fan Yu (Autor), Gan Zhao (Autor), Shuang Geng (Autor), Wencong Yu (Autor), Xuan-Yi Wang (Autor), Bin Wang (Autor)
• Formato: Libro
• Publicado: Taylor & Francis Group, 2020-02-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Regulatory T cells (Tregs) play a crucial role in the control of the initiation and progression of type 1 diabetes (T1D). Various immunological interventions including those to ex vivo expansion Tregs transfer, in vivo induction of peripherally derived Treg (pTreg) have been considered as promising...