Pharmacokinetics of Hydroxyprogesterone Caproate and its Primary Metabolites during Pregnancy

• Main Authors: Kim A. Boggess (Author), Jeffrey B. Baker (Author), Amy P. Murtha (Author), Alan M. Peaceman (Author), Dinesh M. Shah (Author), Sylvia L. Siegfried (Author), Robert Birch (Author)
• 格式: 图书
• 出版: Thieme Medical Publishers, Inc., 2018-04-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Abstract Objective To measure pharmacokinetics of hydroxyprogesterone caproate (OHPC) and its major metabolites throughout pregnancy. Study Design Thirty women were prescribed OHPC for recurrent preterm birth prevention. Three cohorts of subjects had blood drawn for 7 consecutive days at one of thre...