Pharmacokinetics of Hydroxyprogesterone Caproate and its Primary Metabolites during Pregnancy

• Principais autores: Kim A. Boggess (Autor), Jeffrey B. Baker (Autor), Amy P. Murtha (Autor), Alan M. Peaceman (Autor), Dinesh M. Shah (Autor), Sylvia L. Siegfried (Autor), Robert Birch (Autor)
• Formato: Livro
• Publicado em: Thieme Medical Publishers, Inc., 2018-04-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Objective To measure pharmacokinetics of hydroxyprogesterone caproate (OHPC) and its major metabolites throughout pregnancy. Study Design Thirty women were prescribed OHPC for recurrent preterm birth prevention. Three cohorts of subjects had blood drawn for 7 consecutive days at one of thre...