Possible Roles of IL-33 in the Innate-Adaptive Immune Crosstalk of Psoriasis Pathogenesis

• Main Authors: Serafinella Patrizia Cannavò (Author), Lucrezia Bertino (Author), Eleonora Di Salvo (Author), Valeria Papaianni (Author), Elvira Ventura-Spagnolo (Author), Sebastiano Gangemi (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. IL-33 belongs to the IL-1 family, playing a role in several biologic processes as well as in the pathogenesis of different diseases, including skin pathologies. It acts as an alarmin, released by damaged cells. Binding to a ST2 receptor, it stimulates many immune cells such as ILC2 and T...