Possible Roles of IL-33 in the Innate-Adaptive Immune Crosstalk of Psoriasis Pathogenesis

• Автори: Serafinella Patrizia Cannavò (Автор), Lucrezia Bertino (Автор), Eleonora Di Salvo (Автор), Valeria Papaianni (Автор), Elvira Ventura-Spagnolo (Автор), Sebastiano Gangemi (Автор)
• Формат: Книга
• Опубліковано: Hindawi Limited, 2019-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Background. IL-33 belongs to the IL-1 family, playing a role in several biologic processes as well as in the pathogenesis of different diseases, including skin pathologies. It acts as an alarmin, released by damaged cells. Binding to a ST2 receptor, it stimulates many immune cells such as ILC2 and T...