A novel tumor-activated ALA fusion protein for specific inhibition on the growth and invasion of breast cancer cells MDA-MB-231

• Главные авторы: Xiufeng Liu (Автор), Xintong Liu (Автор), Suwen Sunchen (Автор), Meixia Liu (Автор), Chen Shen (Автор), Juanjuan Wu (Автор), Wanli Zhao (Автор), Boyang Yu (Автор), Jihua Liu (Автор)
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• Опубликовано: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Предметы: article
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Objective: The aim of this research was to develop a novel ALA fusion protein for target to the malignant cells surface with high uPAR expression and locally release of the scorpion toxin AGAP in an uPA-cleavable manner. It will provide an effective approach for controlled release of the peptide tox...