A novel tumor-activated ALA fusion protein for specific inhibition on the growth and invasion of breast cancer cells MDA-MB-231

• Egile Nagusiak: Xiufeng Liu (Egilea), Xintong Liu (Egilea), Suwen Sunchen (Egilea), Meixia Liu (Egilea), Chen Shen (Egilea), Juanjuan Wu (Egilea), Wanli Zhao (Egilea), Boyang Yu (Egilea), Jihua Liu (Egilea)
• Formatua: Liburua
• Argitaratua: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Objective: The aim of this research was to develop a novel ALA fusion protein for target to the malignant cells surface with high uPAR expression and locally release of the scorpion toxin AGAP in an uPA-cleavable manner. It will provide an effective approach for controlled release of the peptide tox...