Redox-sensitive lipophilic prodrugs: delivering unstable chemotherapeutant for improved cancer therapy
Therapeutic application of unmodified camptothecin (CPT) is severely restricted by its extremely low water solubility and the instability of active lactone ring. In this study, a redox-sensitive CPT-OA conjugate containing the disulfide bond (CPT-SS-OA) was used to deliver the lactone-stabilized CPT...
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Main Authors: | , , , , , , , , |
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Format: | Book |
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Taylor & Francis Group,
2019-01-01T00:00:00Z.
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Internet
Connect to this object online.3rd Floor Main Library
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A1234.567 |
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Copy 1 | Available |