Gromwell ameliorates glucocorticoid-induced muscle atrophy through the regulation of Akt/mTOR pathway

• Hauptverfasser: Ahyoung Yoo (Verfasst von), Jung-In Kim (Verfasst von), Hyunjung Lee (Verfasst von), Farida S. Nirmala (Verfasst von), Jeong-Hoon Hahm (Verfasst von), Hyo Deok Seo (Verfasst von), Chang Hwa Jung (Verfasst von), Tae Youl Ha (Verfasst von), Jiyun Ahn (Verfasst von)
• Format: Buch
• Veröffentlicht: BMC, 2024-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Abstract Background Muscle atrophy is characterized by decreased muscle mass, function, and strength. Synthetic glucocorticoids, including dexamethasone (Dexa), are commonly used to treat autoimmune diseases. However, prolonged exposure of Dexa with high dose exerts severe side effects, including mu...