Gromwell ameliorates glucocorticoid-induced muscle atrophy through the regulation of Akt/mTOR pathway

• Main Authors: Ahyoung Yoo (Author), Jung-In Kim (Author), Hyunjung Lee (Author), Farida S. Nirmala (Author), Jeong-Hoon Hahm (Author), Hyo Deok Seo (Author), Chang Hwa Jung (Author), Tae Youl Ha (Author), Jiyun Ahn (Author)
• Format: Book
• Published: BMC, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Muscle atrophy is characterized by decreased muscle mass, function, and strength. Synthetic glucocorticoids, including dexamethasone (Dexa), are commonly used to treat autoimmune diseases. However, prolonged exposure of Dexa with high dose exerts severe side effects, including mu...