Gromwell ameliorates glucocorticoid-induced muscle atrophy through the regulation of Akt/mTOR pathway

• Главные авторы: Ahyoung Yoo (Автор), Jung-In Kim (Автор), Hyunjung Lee (Автор), Farida S. Nirmala (Автор), Jeong-Hoon Hahm (Автор), Hyo Deok Seo (Автор), Chang Hwa Jung (Автор), Tae Youl Ha (Автор), Jiyun Ahn (Автор)
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• Опубликовано: BMC, 2024-01-01T00:00:00Z.
• Предметы: article
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Abstract Background Muscle atrophy is characterized by decreased muscle mass, function, and strength. Synthetic glucocorticoids, including dexamethasone (Dexa), are commonly used to treat autoimmune diseases. However, prolonged exposure of Dexa with high dose exerts severe side effects, including mu...