Pharmacological hypotheses: Is acetaminophen selective in its cyclooxygenase inhibition?

Abstract The precise mechanistic action of acetaminophen (ACT; paracetamol) remains debated. ACT's analgesic and antipyretic actions are attributed to cyclooxygenase (COX) inhibition preventing prostaglandin (PG) synthesis. Two COX isoforms (COX1/2) share 60% sequence structure, yet their funct...

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Ngā kaituhi matua: Christopher J. Esh (Author), Bryna C. R. Chrismas (Author), Alexis R. Mauger (Author), Lee Taylor (Author)
Hōputu: Pukapuka
I whakaputaina: Wiley, 2021-08-01T00:00:00Z.
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