Pharmacological hypotheses: Is acetaminophen selective in its cyclooxygenase inhibition?
Abstract The precise mechanistic action of acetaminophen (ACT; paracetamol) remains debated. ACT's analgesic and antipyretic actions are attributed to cyclooxygenase (COX) inhibition preventing prostaglandin (PG) synthesis. Two COX isoforms (COX1/2) share 60% sequence structure, yet their funct...
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Format: | Book |
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Wiley,
2021-08-01T00:00:00Z.
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A1234.567 |
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