Hydrophobic Amino Acid Tryptophan Shows Promise as a Potential Absorption Enhancer for Oral Delivery of Biopharmaceuticals

• Asıl Yazarlar: Noriyasu Kamei (Yazar), Hideyuki Tamiwa (Yazar), Mari Miyata (Yazar), Yuta Haruna (Yazar), Koyo Matsumura (Yazar), Hideyuki Ogino (Yazar), Serena Hirano (Yazar), Kazuhiro Higashiyama (Yazar), Mariko Takeda-Morishita (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2018-10-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Cell-penetrating peptides (CPPs) have great potential to efficiently deliver drug cargos across cell membranes without cytotoxicity. Cationic arginine and hydrophobic tryptophan have been reported to be key component amino acids for cellular internalization of CPPs. We recently found that l-arginine...