Recent progress in discovery of novel AAK1 inhibitors: from pain therapy to potential anti-viral agents

• Asıl Yazarlar: Ying-Hui Yuan (Yazar), Nian-Dong Mao (Yazar), Ji-Long Duan (Yazar), Hang Zhang (Yazar), Carmen Garrido (Yazar), Frédéric Lirussi (Yazar), Yuan Gao (Yazar), Tian Xie (Yazar), Xiang-Yang Ye (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Adaptor associated kinase 1 (AAK1), a member of the Ark1/Prk1 family of Ser/Thr kinases, is a specific key kinase regulating Thr156 phosphorylation at the μ2 subunit of the adapter complex-2 (AP-2) protein. Due to their important biological functions, AAK1 systems have been validated in clinics for...