AZD6738 Inhibits fibrotic response of conjunctival fibroblasts by regulating checkpoint kinase 1/P53 and PI3K/AKT pathways

• Asıl Yazarlar: Longxiang Huang (Yazar), Qin Ye (Yazar), Chunlin Lan (Yazar), Xiaohui Wang (Yazar), Yihua Zhu (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Trabeculectomy can effectively reduce intraocular pressure (IOP) in glaucoma patients, the long-term surgical failure is due to the excessive proliferation and fibrotic response of conjunctival fibroblasts which causes the subconjunctival scar and non-functional filtering bleb. In this study, we dem...