RNAi dynamics in Juvenile Fasciola spp. Liver flukes reveals the persistence of gene silencing in vitro.

• Автори: Paul McVeigh (Автор), Erin M McCammick (Автор), Paul McCusker (Автор), Russell M Morphew (Автор), Angela Mousley (Автор), Abbas Abidi (Автор), Khalid M Saifullah (Автор), Raman Muthusamy (Автор), Ravikumar Gopalakrishnan (Автор), Terry W Spithill (Автор), John P Dalton (Автор), Peter M Brophy (Автор), Nikki J Marks (Автор), Aaron G Maule (Автор)
• Формат: Книга
• Опубліковано: Public Library of Science (PLoS), 2014-09-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Fasciola spp. liver fluke cause pernicious disease in humans and animals. Whilst current control is unsustainable due to anthelmintic resistance, gene silencing (RNA interference, RNAi) has the potential to contribute to functional validation of new therapeutic targets. The susceptibility of juvenil...