Dracorhodin Perchlorate Induces Apoptosis via Activation of Caspases and Generation of Reactive Oxygen Species

• मुख्य लेखकों: Mingyu Xia (लेखक), Dong Wang (लेखक), Minwei Wang (लेखक), Shin-ichi Tashiro (लेखक), Satoshi Onodera (लेखक), Mutsuhiko Minami (लेखक), Takashi Ikejima (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2004-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Dracorhodin perchlorate inhibited proliferation of several tumor cell lines. The drug induced oligonucleosomal fragmentation of DNA in HeLa cells and increased caspase-3, -8, -9 activities followed by the degradation of caspase-3 substrates, inhibitor of caspase-dependent DNase, and poly-(ADP-ribose...