Dracorhodin Perchlorate Induces Apoptosis via Activation of Caspases and Generation of Reactive Oxygen Species

• Príomhchruthaitheoirí: Mingyu Xia (Údar), Dong Wang (Údar), Minwei Wang (Údar), Shin-ichi Tashiro (Údar), Satoshi Onodera (Údar), Mutsuhiko Minami (Údar), Takashi Ikejima (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Elsevier, 2004-01-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Dracorhodin perchlorate inhibited proliferation of several tumor cell lines. The drug induced oligonucleosomal fragmentation of DNA in HeLa cells and increased caspase-3, -8, -9 activities followed by the degradation of caspase-3 substrates, inhibitor of caspase-dependent DNase, and poly-(ADP-ribose...