Hyaluronic acid reduction-sensitive polymeric micelles achieving co-delivery of tumor-targeting paclitaxel/apatinib effectively reverse cancer multidrug resistance

• Hauptverfasser: Xiaoqing Zhang (Verfasst von), Xiaomei Ren (Verfasst von), Jiayin Tang (Verfasst von), Jiangtao Wang (Verfasst von), Xiang Zhang (Verfasst von), Peng He (Verfasst von), Chang Yao (Verfasst von), Weihe Bian (Verfasst von), Lizhu Sun (Verfasst von)
• Format: Buch
• Veröffentlicht: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Multidrug resistance (MDR) of cancer cells is a significant challenge in chemotherapy, highlighting the urgent medical need for simple and reproducible strategies to reverse this process. Here, we report the development of an active tumor-targeting and redox-responsive nanoplatform (PA-ss-NP) using...