Cotinine and 6-Hydroxy-L-Nicotine Reverses Memory Deficits and Reduces Oxidative Stress in Aβ<sub>25-35</sub>-Induced Rat Model of Alzheimer's Disease
The nicotinic derivatives, cotinine (COT), and 6-hydroxy-L-nicotine (6HLN), showed promising cognitive-improving effects without exhibiting the nicotine's side-effects. Here, we investigated the impact of COT and 6HLN on memory impairment and the oxidative stress in the Aβ<sub>25-35</s...
Saved in:
Main Authors: | Razvan Stefan Boiangiu (Author), Marius Mihasan (Author), Dragos Lucian Gorgan (Author), Bogdan Alexandru Stache (Author), Brindusa Alina Petre (Author), Lucian Hritcu (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2020-08-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Anxiolytic, Promnesic, Anti-Acetylcholinesterase and Antioxidant Effects of Cotinine and 6-Hydroxy-L-Nicotine in Scopolamine-Induced Zebrafish (<i>Danio rerio</i>) Model of Alzheimer's Disease
by: Razvan Stefan Boiangiu, et al.
Published: (2021) -
Memory-Enhancing Effects of <i>Origanum majorana</i> Essential Oil in an Alzheimer's Amyloid beta1-42 Rat Model: A Molecular and Behavioral Study
by: Paula Alexandra Postu, et al.
Published: (2020) -
Physiologically Based Pharmacokinetic Modelling for Nicotine and Cotinine Clearance in Pregnant Women
by: Basile Amice, et al.
Published: (2021) -
Effects of the Hydroethanolic Extract of <i>Lycopodium selago</i> L. on Scopolamine-Induced Memory Deficits in Zebrafish
by: Mihai-Vlad Valu, et al.
Published: (2021) -
Bay Leaf (<i>Laurus Nobilis</i> L.) Incense Improved Scopolamine-Induced Amnesic Rats by Restoring Cholinergic Dysfunction and Brain Antioxidant Status
by: Ion Brinza, et al.
Published: (2021)