From PROTAC to TPD: Advances and Opportunities in Targeted Protein Degradation

• Principais autores: Siqi Wang (Autor), Fuchu He (Autor), Chunyan Tian (Autor), Aihua Sun (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2024-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

PROTAC is a rapidly developing engineering technology for targeted protein degradation using the ubiquitin-proteasome system, which has promising applications for inflammatory diseases, neurodegenerative diseases, and malignant tumors. This paper gives a brief overview of the development and design...