Mutual interaction of neurons and astrocytes derived from iPSCs with APP V717L mutation developed the astrocytic phenotypes of Alzheimer's disease

• Главные авторы: Sopak Supakul (Автор), Rei Murakami (Автор), Chisato Oyama (Автор), Tomoko Shindo (Автор), Yuki Hatakeyama (Автор), Maika Itsuno (Автор), Hiroko Bannai (Автор), Shinsuke Shibata (Автор), Sumihiro Maeda (Автор), Hideyuki Okano (Автор)
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• Опубликовано: BMC, 2024-02-01T00:00:00Z.
• Предметы: article
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Abstract Background The development of induced pluripotent stem cells (iPSCs) technology has enabled human cellular disease modeling for inaccessible cell types, such as neural cells in the brain. However, many of the iPSC-derived disease models established to date typically involve only a single ce...