Targeting glutamine utilization to block metabolic adaptation of tumor cells under the stress of carboxyamidotriazole-induced nutrients unavailability

• Những tác giả chính: Jing Shi (Tác giả), Rui Ju (Tác giả), Hongting Gao (Tác giả), Yuqing Huang (Tác giả), Lei Guo (Tác giả), Dechang Zhang (Tác giả)
• Định dạng: Sách
• Được phát hành: Elsevier, 2022-02-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Tumor cells have unique metabolic programming that is biologically distinct from that of corresponding normal cells. Resetting tumor metabolic programming is a promising strategy to ameliorate drug resistance and improve the tumor microenvironment. Here, we show that carboxyamidotriazole (CAI), an a...