Individual co-variation between viral RNA load and gene expression reveals novel host factors during early dengue virus infection of the Aedes aegypti midgut.

• Hoofdauteurs: Vincent Raquin (Auteur), Sarah Hélène Merkling (Auteur), Valérie Gausson (Auteur), Isabelle Moltini-Conclois (Auteur), Lionel Frangeul (Auteur), Hugo Varet (Auteur), Marie-Agnès Dillies (Auteur), Maria-Carla Saleh (Auteur), Louis Lambrechts (Auteur)
• Formaat: Boek
• Gepubliceerd in: Public Library of Science (PLoS), 2017-12-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Dengue virus (DENV) causes more human infections than any other mosquito-borne virus. The current lack of antiviral strategies has prompted genome-wide screens for host genes that are required for DENV infectivity. Earlier transcriptomic studies that identified DENV host factors in the primary vecto...