Individual co-variation between viral RNA load and gene expression reveals novel host factors during early dengue virus infection of the Aedes aegypti midgut.

• Main Authors: Vincent Raquin (Author), Sarah Hélène Merkling (Author), Valérie Gausson (Author), Isabelle Moltini-Conclois (Author), Lionel Frangeul (Author), Hugo Varet (Author), Marie-Agnès Dillies (Author), Maria-Carla Saleh (Author), Louis Lambrechts (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dengue virus (DENV) causes more human infections than any other mosquito-borne virus. The current lack of antiviral strategies has prompted genome-wide screens for host genes that are required for DENV infectivity. Earlier transcriptomic studies that identified DENV host factors in the primary vecto...