A single intraarticular injection of a tranexamic acid-modified hyaluronic acid (HA/TXA) alleviates pain and reduces OA development in a murine model of monosodium iodoacetate-induced osteoarthritis

RationaleTranexamic acid (TXA) is a strong and specific plasminogen activator inhibitor with inhibitory effects on the matrix metalloproteases involved in the pathophysiology of osteoarthritis (OA) through targeting of the fibrinolysis pathway. In this study, we evaluated the analgesic and chondropr...

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Main Authors: Sybille Brochard (Author), Karim Boumédiene (Author), Jéromine Mercier (Author), Véronique Agin (Author), Thierry Conrozier (Author), Catherine Baugé (Author)
Format: Book
Published: Frontiers Media S.A., 2024-09-01T00:00:00Z.
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3rd Floor Main Library

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