Therapeutic Treatment of Arthritic Mice with 15-Deoxy Δ12,14-Prostaglandin J2 (15d-PGJ2) Ameliorates Disease through the Suppression of Th17 Cells and the Induction of CD4+CD25−FOXP3+ Cells

• Үндсэн зохиолчид: Vanessa Carregaro (Зохиогч), Marcelo H. Napimoga (Зохиогч), Raphael S. Peres (Зохиогч), Luciana Benevides (Зохиогч), Laís Amorim Sacramento (Зохиогч), Larissa G. Pinto (Зохиогч), Renata Grespan (Зохиогч), Thiago M. Cunha (Зохиогч), João Santana da Silva (Зохиогч), Fernando Q. Cunha (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Hindawi Limited, 2016-01-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

The prostaglandin, 15-deoxy Δ12,14-prostaglandin J2 (15d-PGJ2), is a lipid mediator that plays an important role in the control of chronic inflammatory disease. However, the role of prostanoid in rheumatoid arthritis (RA) is not well determined. We demonstrated the therapeutic effect of 15d-PGJ2 in...