Stability of Methylphenidate under Various pH Conditions in the Presence or Absence of Gut Microbiota

• Main Authors: Julia Aresti-Sanz (Author), Markus Schwalbe (Author), Rob Rodrigues Pereira (Author), Hjalmar Permentier (Author), Sahar El Aidy (Author)
• פורמט: ספר
• יצא לאור: MDPI AG, 2021-07-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Methylphenidate is one of the most widely used oral treatments for attention-deficit/hyperactivity disorder (ADHD). The drug is mainly absorbed in the small intestine and has low bioavailability. Accordingly, a high interindividual variability in terms of response to the treatment is known among ADH...