Amiodarone reduces depolarization-evoked glutamate release from hippocampual synaptosomes
Decreased brain glutamate level has emerged as a new therapeutic approach for epilepsy. This study investigated the effect and mechanism of amiodarone, an anti-arrhythmic drug with antiepileptic activity, on glutamate release in the rat hippocampus. In a synaptosomal preparation, amiodarone reduced...
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Main Authors: | Chia Yu Chang (Author), Chi Feng Hung (Author), Shu Kuei Huang (Author), Jinn Rung Kuo (Author), Su Jane Wang (Author) |
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Format: | Book |
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Elsevier,
2017-03-01T00:00:00Z.
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