Age-related changes of protein SUMOylation balance in the AβPP Tg2576 mouse model of Alzheimer's disease

• Main Authors: Robert eNisticò (Author), Caterina eFerraina (Author), Veronica eMarconi (Author), Fabio eBlandini (Author), Lucia eNegri (Author), Jan eEgebjerg (Author), Marco eFeligioni (Author)
• Format: Book
• Published: Frontiers Media S.A., 2014-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Alzheimer's disease (AD) is a complex disorder that affects the central nervous system causing a severe neurodegeneration. This pathology affects an increasing number of people worldwide due to the overall aging of the human population. In recent years SUMO protein modification has emerged as a...