Age-related changes of protein SUMOylation balance in the AβPP Tg2576 mouse model of Alzheimer's disease

• Auteurs principaux: Robert eNisticò (Auteur), Caterina eFerraina (Auteur), Veronica eMarconi (Auteur), Fabio eBlandini (Auteur), Lucia eNegri (Auteur), Jan eEgebjerg (Auteur), Marco eFeligioni (Auteur)
• Format: Livre
• Publié: Frontiers Media S.A., 2014-04-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Alzheimer's disease (AD) is a complex disorder that affects the central nervous system causing a severe neurodegeneration. This pathology affects an increasing number of people worldwide due to the overall aging of the human population. In recent years SUMO protein modification has emerged as a...