Age-related changes of protein SUMOylation balance in the AβPP Tg2576 mouse model of Alzheimer's disease

• Автори: Robert eNisticò (Автор), Caterina eFerraina (Автор), Veronica eMarconi (Автор), Fabio eBlandini (Автор), Lucia eNegri (Автор), Jan eEgebjerg (Автор), Marco eFeligioni (Автор)
• Формат: Книга
• Опубліковано: Frontiers Media S.A., 2014-04-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Alzheimer's disease (AD) is a complex disorder that affects the central nervous system causing a severe neurodegeneration. This pathology affects an increasing number of people worldwide due to the overall aging of the human population. In recent years SUMO protein modification has emerged as a...