Nobiletin protects against alcohol-induced mitochondrial dysfunction and liver injury by regulating the hepatic NRF1-TFAM signaling pathway

• প্রধান লেখক: Dan Lu (লেখক), Aiping Huang (লেখক), Xiaoqing Tong (লেখক), Xiaoyan Zhang (লেখক), Songtao Li (লেখক), Xiaolong Yu (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Objectives Alcohol and its metabolites, such as acetaldehyde, induced hepatic mitochondrial dysfunction play a pathological role in the development of alcohol-related liver disease (ALD).Methods In this study, we investigated the potential of nobiletin (NOB), a polymethoxylated flavone, to counter a...