Soyasaponins reduce inflammation by downregulating MyD88 expression and suppressing the recruitments of TLR4 and MyD88 into lipid rafts

• Main Authors: Junbin Chen (Author), Hidayat Ullah (Author), Zhongdaixi Zheng (Author), Xiangfu Gu (Author), Chuhong Su (Author), Lingyu Xiao (Author), Xinglong Wu (Author), Fei Xiong (Author), Qing Li (Author), Longying Zha (Author)
• Format: Book
• Published: BMC, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Previous studies indicate that soyasaponins may reduce inflammation via modulating toll-like receptor 4 (TLR4)/myeloid differentiation factor 88 (MyD88) signaling. However, its underlying mechanisms are still not fully understood. Methods Lipopolysaccharide (LPS)-challenged infla...