Soyasaponins reduce inflammation by downregulating MyD88 expression and suppressing the recruitments of TLR4 and MyD88 into lipid rafts

• मुख्य लेखकों: Junbin Chen (लेखक), Hidayat Ullah (लेखक), Zhongdaixi Zheng (लेखक), Xiangfu Gu (लेखक), Chuhong Su (लेखक), Lingyu Xiao (लेखक), Xinglong Wu (लेखक), Fei Xiong (लेखक), Qing Li (लेखक), Longying Zha (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2020-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Previous studies indicate that soyasaponins may reduce inflammation via modulating toll-like receptor 4 (TLR4)/myeloid differentiation factor 88 (MyD88) signaling. However, its underlying mechanisms are still not fully understood. Methods Lipopolysaccharide (LPS)-challenged infla...