Mutant Huntingtin Derails Cysteine Metabolism in Huntington's Disease at Both Transcriptional and Post-Translational Levels

• मुख्य लेखकों: Bindu D. Paul (लेखक), Juan I. Sbodio (लेखक), Solomon H. Snyder (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-07-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Cysteine is a semi-essential amino acid that not only plays an essential role as a component of protein synthesis, but also in the generation of numerous sulfur-containing molecules such as the antioxidant glutathione and coenzyme A. We previously showed that the metabolism of cysteine is dysregulat...