Mutant Huntingtin Derails Cysteine Metabolism in Huntington's Disease at Both Transcriptional and Post-Translational Levels

• Hoofdauteurs: Bindu D. Paul (Auteur), Juan I. Sbodio (Auteur), Solomon H. Snyder (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2022-07-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Cysteine is a semi-essential amino acid that not only plays an essential role as a component of protein synthesis, but also in the generation of numerous sulfur-containing molecules such as the antioxidant glutathione and coenzyme A. We previously showed that the metabolism of cysteine is dysregulat...