Intrachromosomal amplification, locus deletion and point mutation in the aquaglyceroporin AQP1 gene in antimony resistant Leishmania (Viannia) guyanensis.

BACKGROUND:Antimony resistance complicates the treatment of infections caused by the parasite Leishmania. METHODOLOGY/PRINCIPAL FINDINGS:Using next generation sequencing, we sequenced the genome of four independent Leishmania guyanensis antimony-resistant (SbR) mutants and found different chromosoma...

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主要な著者: Rubens Monte-Neto (著者), Marie-Claude N Laffitte (著者), Philippe Leprohon (著者), Priscila Reis (著者), Frédéric Frézard (著者), Marc Ouellette (著者)
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出版事項: Public Library of Science (PLoS), 2015-02-01T00:00:00Z.
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3rd Floor Main Library

予約・返却請求 3rd Floor Main Library
請求記号: A1234.567
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