Identifying potential therapeutic targets in lung adenocarcinoma: a multi-omics approach integrating bulk and single-cell RNA sequencing with Mendelian randomization

• मुख्य लेखकों: Youpeng Chen (लेखक), Enzhong Li (लेखक), Zhenglin Chang (लेखक), Tingting Zhang (लेखक), Zhenfeng Song (लेखक), Haojie Wu (लेखक), Zhangkai J. Cheng (लेखक), Baoqing Sun (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2024-07-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Our research aimed to identify new therapeutic targets for Lung adenocarcinoma (LUAD), a major subtype of non-small cell lung cancer known for its low 5-year survival rate of 22%. By employing a comprehensive methodological approach, we analyzed bulk RNA sequencing data from 513 LUAD and 59 non-tumo...