Identifying potential therapeutic targets in lung adenocarcinoma: a multi-omics approach integrating bulk and single-cell RNA sequencing with Mendelian randomization

• Үндсэн зохиолчид: Youpeng Chen (Зохиогч), Enzhong Li (Зохиогч), Zhenglin Chang (Зохиогч), Tingting Zhang (Зохиогч), Zhenfeng Song (Зохиогч), Haojie Wu (Зохиогч), Zhangkai J. Cheng (Зохиогч), Baoqing Sun (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Frontiers Media S.A., 2024-07-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Our research aimed to identify new therapeutic targets for Lung adenocarcinoma (LUAD), a major subtype of non-small cell lung cancer known for its low 5-year survival rate of 22%. By employing a comprehensive methodological approach, we analyzed bulk RNA sequencing data from 513 LUAD and 59 non-tumo...