Identifying potential therapeutic targets in lung adenocarcinoma: a multi-omics approach integrating bulk and single-cell RNA sequencing with Mendelian randomization

• Main Authors: Youpeng Chen (Author), Enzhong Li (Author), Zhenglin Chang (Author), Tingting Zhang (Author), Zhenfeng Song (Author), Haojie Wu (Author), Zhangkai J. Cheng (Author), Baoqing Sun (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Our research aimed to identify new therapeutic targets for Lung adenocarcinoma (LUAD), a major subtype of non-small cell lung cancer known for its low 5-year survival rate of 22%. By employing a comprehensive methodological approach, we analyzed bulk RNA sequencing data from 513 LUAD and 59 non-tumo...