A Novel Small Molecule Which Increases Osteoprotegerin Expression and Protects Against Ovariectomy-Related Bone Loss in Rats

• Hoofdauteurs: Xiaowan Han (Auteur), Shiqiang Gong (Auteur), Ni Li (Auteur), Xiao Wang (Auteur), Peng Liu (Auteur), Yanni Xu (Auteur), Xiaobo He (Auteur), Wei Jiang (Auteur), Shuyi Si (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2019-03-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

The ratio of osteoprotegerin (OPG) to the receptor activator of NF-κB ligand (RANKL) is a key determinant in the regulation of bone metabolism. The study was performed to screen novel anti-osteoporotic drugs regulating OPG/RANKL ratio and evaluate their effect on bone metabolism. According to the sc...