Activation of dopamine receptor D1 promotes osteogenic differentiation and reduces glucocorticoid-induced bone loss by upregulating the ERK1/2 signaling pathway

• Κύριοι συγγραφείς: Jie Zhu (Συγγραφέας), Chengcheng Feng (Συγγραφέας), Weicheng Zhang (Συγγραφέας), Zhidong Wang (Συγγραφέας), Mengdan Zhong (Συγγραφέας), Wenkai Tang (Συγγραφέας), Zhifang Wang (Συγγραφέας), Haiwei Shi (Συγγραφέας), Zhengyu Yin (Συγγραφέας), Jiandong Shi (Συγγραφέας), Yu Huang (Συγγραφέας), Long Xiao (Συγγραφέας), Dechun Geng (Συγγραφέας), Zhirong Wang (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: BMC, 2022-02-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Abstract Background The inhibition of osteogenic differentiation is a major factor in glucocorticoid-induced bone loss, but there is currently no effective treatment. Dopamine, a major neurotransmitter, transmits signals via five different seven-transmembrane G protein-coupled receptors termed D1 to...