Cerebellar Vermis and Midbrain Hypoplasia Upon Conditional Deletion of Chd7 from the Embryonic Mid-Hindbrain Region

Cerebellar Vermis and Midbrain Hypoplasia Upon Conditional Deletion of Chd7 from the Embryonic Mid-Hindbrain Region

Reduced fibroblast growth factor (FGF) signaling from the mid-hindbrain or isthmus organizer (IsO) during early embryonic development results in hypoplasia of the midbrain and cerebellar vermis. We previously reported evidence for reduced Fgf8 expression and FGF signaling in the mid-hindbrain region...

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Main Authors: Alex P. A. Donovan (Author), Tian Yu (Author), Jacob Ellegood (Author), Kimberley L. H. Riegman (Author), Christa de Geus (Author), Conny van Ravenswaaij-Arts (Author), Cathy Fernandes (Author), Jason P. Lerch (Author), M. Albert Basson (Author)
Format: Book
Published: Frontiers Media S.A., 2017-10-01T00:00:00Z.
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3rd Floor Main Library

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