Molecular variation of Plasmodium vivax dehydrofolate reductase in Mexico and Nicaragua contrasts with that occurring in South America

• Main Authors: Lilia González-Cerón (Author), Mario H Rodríguez (Author), Alberto Montoya (Author), Frida Santillán-Valenzuela (Author), Josselin C Corzo-Gómez (Author)
• Format: Book
• Published: Instituto Nacional de Salud Pública, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective. To research mutations associated to pyrimetha­mine resistance in dihydrofolate reductase (pvdhfr) of Plasmo­dium vivax from Mexico and Nicaragua and compare it to that reported in the rest of America. Materials and methods. Genomic DNA was obtained from P. vivax-infected blood sam­ples. A...