Molecular variation of Plasmodium vivax dehydrofolate reductase in Mexico and Nicaragua contrasts with that occurring in South America

• Hauptverfasser: Lilia González-Cerón (Verfasst von), Mario H Rodríguez (Verfasst von), Alberto Montoya (Verfasst von), Frida Santillán-Valenzuela (Verfasst von), Josselin C Corzo-Gómez (Verfasst von)
• Format: Buch
• Veröffentlicht: Instituto Nacional de Salud Pública, 2020-06-01T00:00:00Z.
• Schlagworte: article
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Objective. To research mutations associated to pyrimetha­mine resistance in dihydrofolate reductase (pvdhfr) of Plasmo­dium vivax from Mexico and Nicaragua and compare it to that reported in the rest of America. Materials and methods. Genomic DNA was obtained from P. vivax-infected blood sam­ples. A...