ECNano: A cost-effective workflow for target enrichment sequencing and accurate variant calling on 4800 clinically significant genes using a single MinION flowcell

• Asıl Yazarlar: Amy Wing-Sze Leung (Yazar), Henry Chi-Ming Leung (Yazar), Chak-Lim Wong (Yazar), Zhen-Xian Zheng (Yazar), Wui-Wang Lui (Yazar), Ho-Ming Luk (Yazar), Ivan Fai-Man Lo (Yazar), Ruibang Luo (Yazar), Tak-Wah Lam (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: BMC, 2022-03-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Background The application of long-read sequencing using the Oxford Nanopore Technologies (ONT) MinION sequencer is getting more diverse in the medical field. Having a high sequencing error of ONT and limited throughput from a single MinION flowcell, however, limits its applicability for ac...